Human and Other organisms Genotyping

This unit offers a large variety of platforms to human and other organisms Genotyping and a customized platform could be employed according to user needs and depends of the objetive of the study.

Single nucleotide polymorphisms (SNPs) and copy number polymorphisms (CNPs) assays are available using high-throughput detection systems. SNPs are the most common type of genetic variation in the human genome and could predispose people to disease (Human diagnosis) or influence their response to a drug (Pharmacogenetic). However, structural variation changes, such as deletion and duplications, referred to as CNPs are proving to be more common than expected. In animals and plants, SNPs also play an important role in the study of genetic variations within a population (Characterisation of genetic variability and Genetic improvement).

Addtional fragment analysis can be develop in our facilities. On the one hand, STRs (Short Tandem Repeats) or MPLAs (Multiplex Ligation-dependent Probe Amplification) assays, which can be used for Pedigree test and Detections of large delections or duplications in genomic DNA, respectively. On the other hand, AFLPs (Amplified Fragment Lengh Polymorphism) or MLST (Multi Locus Sequence Typing) assays are also avaible, and are widely used for Animal and plants identifications and Microbial typification, respectively.

Addtional software and Databases: depending of user needs, different softwares and databases such as Mutation Surveyor^©, Alamut^©, Genevestigator^© or Ingenuity Pathways Analysis (IPA^©) are offered to enhance the studies.