Chip-Seq

The combination of chromatin imunoprecipitación technique (chip) with the sequencing of the DNA fragments associated, allows information about the protein-DNA interactions along the entire genome and its regulation expressions to understand many biological processes and disease states. It determines whether specific proteins are associated with specific genomic regions, such as transcription factors on promoters or other DNA binding sites.

High-throughput sequencing on Illumina NextSeq 550 provides the ideal sequencing platform for ChIP experiments. Chip-seq library construct is done by Illumina TruSeq ChIP Sample Preparation Kits. 

This service is only applicable in ChIP samples provided by our clients and allows us to:

• Identification of DNA binding sites of transcription factors and other, chromatin associated proteins
• Mapping of DNA binding sites of histone modifiers

Sequencing Platform: Illumina NextSeq 550.